Expanding the Mammalian Phenotype Ontology to Meet the Needs of COVID-19 Model Curation

Through the course of the COVID-19 pandemic a wide array of signs and symptoms displayed by patients have been identified. Mouse models of COVID-19 display phenotypes that correlate to many of these signs and symptoms. To capture the phenotypes of these mouse models in the Mouse Genome Informatics database the Mammalian Phenotype (MP) ontology was reviewed to map these symptoms to existing MP terms and add new terms where needed. This review identified over 350 COVID-19 signs and symptoms and resulted in the addition of 127 new MP terms. © 2021 Copyright for this paper by its authors.